Oxford Cancer Trials

Engineering and improving anti-CTLA-4 checkpoint inhibitors.

Galvez-Cancino F. et al, (2026), Clin Cancer Res

Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023).

Perletta V. et al, (2026), ESMO Real World Data Digit Oncol, 12

Durvalumab Plus Paclitaxel, with or without Capivasertib or Oleclumab, in Patients with Locally Advanced/Metastatic Triple-Negative Breast Cancer.

Schmid P. et al, (2026), Clin Cancer Res

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis.

Beernaert B. et al, (2026), Sci Adv, 12

TMEM33 deletion potentiates anti-tumor CD8+ T cell immunity.

Jackson MT. et al, (2026)

Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology.

Phillips R. et al, (2026), Br J Cancer, 134, 289 - 294

Clinical Impact of Next-Generation Sequencing-Guided Targeted Therapies in Advanced Cancer: A Systematic Review and Meta-Analysis.

Kazmi F. et al, (2025), Clin Oncol (R Coll Radiol), 48

Single-cell proteomics sheds light on neutrophil diversity in glioblastoma.

Skolariki A. and Parkes EE., (2025), Nat Rev Immunol, 25

A First-in-Class mAb (BI-1607) Targeting FcγRIIB: Preclinical Data and First-in-Human Studies in Patients with HER2-Positive Advanced Solid Tumors.

Cortés J. et al, (2025), Clin Cancer Res, 31, 4953 - 4963

Figure 5 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Cheng VWT. et al, (2025)

Figure 4 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Cheng VWT. et al, (2025)

Data from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Cheng VWT. et al, (2025)

Figure 1 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Cheng VWT. et al, (2025)

Figure 3 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Cheng VWT. et al, (2025)

Figure 2 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Cheng VWT. et al, (2025)

Figure 6 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Cheng VWT. et al, (2025)

IGF-1 regulates cancer cell immune evasion in prostate cancer.

Nandakumar AM. et al, (2025), Sci Rep, 15

Replication-Competent, Tumor-Specific Immuno-Gene Vectors Allow for Exchange of Transgenes and Lead to Viral Persistence Following IV Administration.

Rosen LS. et al, (2025), J Immunother Precis Oncol, 8, 263 - 275

Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis.

Pinho MP. et al, (2025), Cell Rep Med, 6

Interactions between cancer-associated fibroblasts and the extracellular matrix in oesophageal cancer.

Vadibeler S. et al, (2025), Matrix Biol, 139, 49 - 60

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Engineering and improving anti-CTLA-4 checkpoint inhibitors.

Real-world obesity prevalence and history in 79 271 patients receiving systemic anticancer therapy across 13 cancer types in England (2013-2023).

Durvalumab Plus Paclitaxel, with or without Capivasertib or Oleclumab, in Patients with Locally Advanced/Metastatic Triple-Negative Breast Cancer.

Chromosomal instability shapes the tumor microenvironment of esophageal adenocarcinoma via a cGAS-chemokine-myeloid axis.

TMEM33 deletion potentiates anti-tumor CD8+ T cell immunity.

Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology.

Clinical Impact of Next-Generation Sequencing-Guided Targeted Therapies in Advanced Cancer: A Systematic Review and Meta-Analysis.

Single-cell proteomics sheds light on neutrophil diversity in glioblastoma.

A First-in-Class mAb (BI-1607) Targeting FcγRIIB: Preclinical Data and First-in-Human Studies in Patients with HER2-Positive Advanced Solid Tumors.

Figure 5 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Figure 4 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Data from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Figure 1 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Figure 3 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Figure 2 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

Figure 6 from VCAM-1–targeted MRI Improves Detection of the Tumor-brain Interface

IGF-1 regulates cancer cell immune evasion in prostate cancer.

Replication-Competent, Tumor-Specific Immuno-Gene Vectors Allow for Exchange of Transgenes and Lead to Viral Persistence Following IV Administration.

Tumor-specific CD8 T cell characterization in HR+ breast cancer reveals an impaired antitumoral response in patients with lymph node metastasis.

Interactions between cancer-associated fibroblasts and the extracellular matrix in oesophageal cancer.

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