Single-Cell Multiomic Profiling of TP53 Mutated Myelodysplastic Neoplasms- All Clones Are Not Equal
Chowdhury O. et al, (2024), BLOOD, 144, 3615 - 3616
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
Luis TC. et al, (2023), Nature Communications, 14
Diagnosis and evaluation of prognosis of myelofibrosis: A British Society for Haematology Guideline.
McLornan DP. et al, (2023), Br J Haematol
Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts.
Moura PL. et al, (2023), Cancer research
RAS-pathway mutations are common in patients with ruxolitinib refractory/intolerant myelofibrosis: molecular analysis of the PAC203 cohort.
O'Sullivan JM. et al, (2023), Leukemia
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.
Luis TC. et al, (2023), Nat Commun, 14
Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.
Rodriguez-Meira A. et al, (2023), Nat Genet
Ruxolitinib Versus Best Available Therapy for Polycythemia Vera Intolerant or Resistant to Hydroxycarbamide in a Randomized Trial.
Harrison CN. et al, (2023), J Clin Oncol
MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis.
Mascarenhas J. et al, (2023), J Clin Oncol
Correction: Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients.
Ryou H. et al, (2023), Leukemia
CHROMOTHRIPSIS AND LEUKEMIC TRANSFORMATION IN MPN
Brierley C. et al, (2023), EXPERIMENTAL HEMATOLOGY, 124, S65 - S65
Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A
Brierley CK. et al, (2023), BLOOD, 142
Platelets Sequester Extracellular DNA, Capturing Tumour-Derived and Free Fetal DNA
Murphy L. et al, (2023), BLOOD, 142
Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia.
Rastogi N. et al, (2022), Leukemia
Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients
HARRINGTON H. et al, (2022), Leukemia
Contribution of mutant HSC clones to immature and mature cells in MDS and CMML, and variations with AZA therapy.
Schnegg-Kaufmann AS. et al, (2022), Blood
CNL and aCML should be considered as single entity based on molecular profiles and outcomes.
Carreño-Tarragona G. et al, (2022), Blood Adv
Single-cell methods in myeloproliferative neoplasms - old questions, new technologies.
O'Sullivan JM. et al, (2022), Blood
MPN-238 Single-Cell RNA Profiling of Myelofibrosis Patients Reveals Pelabresib-Induced Decrease of Megakaryocytic Progenitors and Normalization of CD4+ T Cells in Peripheral Blood.
Zavidij O. et al, (2022), Clin Lymphoma Myeloma Leuk, 22 Suppl 2, S331 - S332