Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Publications

Robust CRISPR/dCas13 RNA blockers specifically perturb miRNA-target interactions and rescue type 1 myotonic dystrophy pathology

Hanifi M. et al, (2024)

RUX-AZA Response in AP/BP-MPN Is Driven By Release of the Differentiation Block in Mutant HSPCs: A Single-Cell Multi-Omic Analysis of Responders on the Phase Ib Phazar Study

Brierley CK. et al, (2024), BLOOD, 144, 3146 - 3147

Single-Cell Multiomic Profiling of TP53 Mutated Myelodysplastic Neoplasms- All Clones Are Not Equal

Chowdhury O. et al, (2024), BLOOD, 144, 3615 - 3616

Spatial Transcriptomics Identifies Aberrant Communication between Dendritic Cells and Leukemia Stem Cells As a Therapeutically Targetable Axis in Juvenile Myelomonocytic Leukemia

Louka E. et al, (2024), BLOOD, 144, 822 - 823

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner

Luis TC. et al, (2023), Nature Communications, 14

Diagnosis and evaluation of prognosis of myelofibrosis: A British Society for Haematology Guideline.

McLornan DP. et al, (2023), Br J Haematol

Erythroid differentiation enhances RNA mis-splicing in SF3B1-mutant myelodysplastic syndromes with ring sideroblasts.

Moura PL. et al, (2023), Cancer research

RAS-pathway mutations are common in patients with ruxolitinib refractory/intolerant myelofibrosis: molecular analysis of the PAC203 cohort.

O'Sullivan JM. et al, (2023), Leukemia

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner.

Luis TC. et al, (2023), Nat Commun, 14

Single-cell multi-omics identifies chronic inflammation as a driver of TP53-mutant leukemic evolution.

Rodriguez-Meira A. et al, (2023), Nat Genet

Ruxolitinib Versus Best Available Therapy for Polycythemia Vera Intolerant or Resistant to Hydroxycarbamide in a Randomized Trial.

Harrison CN. et al, (2023), J Clin Oncol

MANIFEST: Pelabresib in Combination With Ruxolitinib for Janus Kinase Inhibitor Treatment-Naïve Myelofibrosis.

Mascarenhas J. et al, (2023), J Clin Oncol

Correction: Continuous Indexing of Fibrosis (CIF): improving the assessment and classification of MPN patients.

Ryou H. et al, (2023), Leukemia

CHROMOTHRIPSIS AND LEUKEMIC TRANSFORMATION IN MPN

Brierley C. et al, (2023), EXPERIMENTAL HEMATOLOGY, 124, S65 - S65

Chromothripsis Orchestrates Leukemic Transformation in Blast Phase MPN through Targetable Amplification of DYRK1A

Brierley CK. et al, (2023), BLOOD, 142

Erythroid differentiation intensifies RNA mis-splicing inSF3B1-mutant myelodysplastic syndromes with ring sideroblasts

Moura P. et al, (2023)

Platelets Sequester Extracellular DNA, Capturing Tumour-Derived and Free Fetal DNA

Murphy L. et al, (2023), BLOOD, 142

Tamoxifen reduces mitochondrial respiration, oncogenic signaling and mutant allele burden in a myeloproliferative neoplasm subset

Fang Z. et al, (2023)

Nuclear factor I-C overexpression promotes monocytic development and cell survival in acute myeloid leukemia.

Rastogi N. et al, (2022), Leukemia

Continuous Indexing of Fibrosis (CIF): improving the assessment and classiﬁcation of MPN patients

HARRINGTON H. et al, (2022), Leukemia

1
2
3
4
5
6
7
...
»