Whole-genome sequencing of a sporadic primary immunodeficiency cohort.
Thaventhiran JED. et al, (2020), Nature, 583, 90 - 95
Whole-genome sequencing of patients with rare diseases in a national health system.
Turro E. et al, (2020), Nature, 583, 96 - 102
A NOVEL IN VITRO PLATFORM FOR THE PRIORITISATION AND VALIDATION OF INHIBITORS OF BONE MARROW FIBROSIS USING HUMAN BONE MARROW (BM) STROMAL CELLS
COLOMBO M. et al, (2020), HemaSphere, 4, 1 - 1168
SINGLE-CELL MULTI-OMICS REVEALS ABERRANT MEGAKARYOCYTE-PROGENITOR (MKP) SUB-FRACTIONS IN MYELOFIBROSIS (MF) AND IDENTIFIES MUTANT CLONE-SPECIFIC TARGETS
PSAILA B. et al, (2020), HemaSphere, 4, 1 - 1168
Enhanced engraftment of human myelofibrosis stem and progenitor cells in MISTRG mice.
Lysenko V. et al, (2020), Blood Adv, 4, 2477 - 2488
Rapid Emergence of Chronic Lymphocytic Leukemia During JAK2 Inhibitor Therapy in a Patient With Myelofibrosis.
Sousos N. et al, (2020), Hemasphere, 4
Real-world tyrosine kinase inhibitor treatment pathways, monitoring patterns and responses in patients with chronic myeloid leukaemia in the United Kingdom: the UK TARGET CML study
MEAD A., (2020), British Journal of Haematology
Red cell transfusion in outpatients with myelodysplastic syndromes: a feasibility and exploratory randomised trial.
Stanworth SJ. et al, (2020), Br J Haematol, 189, 279 - 290
Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia.
Louka E. et al, (2020), BioRix
Single-cell analyses reveal aberrant pathways for megakaryocyte-biased hematopoiesis in myelofibrosis and identify mutant clone-specific targets
ROBERTS I. et al, (2020), Molecular Cell
A physician survey on the application of the British Society for Haematology guidelines for the diagnosis and management of myelofibrosis in the UK.
Harrison CN. et al, (2020), British journal of haematology, 188, e105 - e109
Single-cell sequencing in hematology.
Brierley CK. and Mead AJ., (2020), Current opinion in oncology, 32, 139 - 145
The quiescent fraction of chronic myeloid leukemic stem cells depends on BMPR1B, Stat3 and BMP4-niche signals to persist in patients in remission.
Jeanpierre S. et al, (2020), Haematologica, 106, 111 - 122
An ontogenetic switch drives the positive and negative selection of B cells
CORNALL R. et al, (2020), PNAS
Technological advances and computational approaches for alternative splicing analysis in single cells.
Wen WX. et al, (2020), Comput Struct Biotechnol J, 18, 332 - 343
The poor outcome in high molecular risk, hydroxycarbamide-resistant/intolerant ET is not ameliorated by ruxolitinib.
O'Sullivan JM. et al, (2019), Blood, 134, 2107 - 2111
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.
Di Genua C. et al, (2019), Haematologica, 104, 2215 - 2224
Low-dose methotrexate: potential clinical impact on haematological and constitutional symptoms in myeloproliferative neoplasms.
Francis S. et al, (2019), Br J Haematol, 187, e69 - e72
Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs.
O'Byrne S. et al, (2019), Blood, 134, 1059 - 1071